Ruhr-Universität Bochum

Anatomie und Molekulare Embryologie

ATOH8

Ninfa Fragale

ATOH8 in Zebrafish: „Small fry” with Great Perspectives

Small fry:
1. young children
2. young or small fishes
3. people/things regarded as unimportant
(collinsdictionary.com)

When it comes to zebrafish, there is no such thing as being “regarded as unimportant”. In the past decades, the popularity of the small fresh water fish as a model organism in medical and scientific research has risen enormously.

… got curious? Find out more about research opportunities with zebrafish

Selected publications

Fragale N, Divvela SSK, Brand-Saberi B. (2021) Atoh8 expression pattern in early zebrafish embryonic development. Histochem Cell Biol. doi: 10.1007/s00418-021-02001-z. PMID: 34120256.

Schroeder N, Wuelling M, Hoffmann D, Brand-Saberi B, Vortkamp A. (2019) Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones. PLoS One. 14(8):e0218230. PMID: 3144952

Divvela SSK, Nell P, Napirei M, Zaehres H, Chen J, Gerding WM, Nguyen HP, Gao S, Brand-Saberi B. (2019) bHLH Transcription Factor Math6 Antagonizes TGF-β Signalling in Reprogramming, Pluripotency and Early Cell Fate Decisions. Cells. 8(6):529. PMID: 31159500

Böing M, Brand-Saberi B, Napirei M. (2018) Murine transcription factor Math6 is a regulator of placenta development. Sci Rep. 8(1):14997. PMID: 30301918

Chen J, Balakrishnan-Renuka A, Hagemann N, Theiss C, Chankiewitz V, Chen J, Pu Q, Erdmann KS, Brand-Saberi B. (2016) A novel interaction between ATOH8 and PPP3CB. Histochem Cell Biol. 145(1):5-16 PMID: 26496921

Wang B, Balakrishnan-Renuka A, Napirei M, Theiss C, Brand-Saberi B. (2015) Spatiotemporal expression of Math6 during mouse embryonic development. Histochem Cell Biol. 143(6):575-82. PMID: 25578518.

Güttsches AK, Balakrishnan-Renuka A, Kley RA, Tegenthoff M, Brand-Saberi B, Vorgerd M. (2015) ATOH8: a novel marker in human muscle fiber regeneration. Histochem Cell Biol. 143(5):443-52. PMID: 25514850.

Balakrishnan-Renuka A, Morosan-Puopolo G, Yusuf F, Abduelmula A, Chen J, Zoidl G, Philippi S, Dai F, Brand-Saberi B. (2014) ATOH8, a regulator of skeletal myogenesis in the hypaxial myotome of the trunk. Histochem Cell Biol. 141(3):289-300. PMID: 24186058

Chen J, Dai F, Balakrishnan-Renuka A, Leese F, Schempp W, Schaller F, Hoffmann MM, Morosan-Puopolo G, Yusuf F, Bisschoff IJ, Chankiewitz V, Xue J, Chen J, Ying K, Brand-Saberi B. (2011) Diversification and molecular evolution of ATOH8, a gene encoding a bHLH transcription factor. PLoS One 6(8):e23005. PMID: 21857980

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